Across TCGA pan-cancer cohorts, FAR1-IT1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FAR1-IT1’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where FAR1-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAR1-IT1 is over-expressed in tumor.
BLCA, CHOL, and KIRC are the cancer types where FAR1-IT1 tumor–normal differential expression is most reproducible.