FAP

Across TCGA patient cohorts, FAP RNA expression is significantly associated with the protein abundance of many other proteins, with 23,128 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAP-associated proteins across cancer lineages are POSTN, CALD1, and CCDC80. Each is linked with FAP in more than 9 cancer types. Because this analysis shows association rather than direction, both FAP-to-partner and partner-to-FAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAP versus POSTN in OV, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAP→partner) and Y-score (partner→FAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	POSTN →	+1.171	+2.112	<.001	<.001	3	10
UCEC	CALD1 →	+0.911	+1.057	<.001	<.001	3	10
OV	CCDC80 →	+1.159	+2.393	<.001	<.001	3	10
OV	CNN2 →	+1.030	+2.420	<.001	<.001	3	10
BRCA	COL3A1 →	+0.963	+1.716	<.001	<.001	3	10
BRCA	COL5A2 →	+1.136	+1.635	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,128 associations by consensus.

FAP vs POSTN — OV

Explore this scatter interactively →