FAP

Across TCGA patient cohorts, FAP protein abundance is significantly associated with the protein abundance of many other proteins, with 25,371 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAP-associated proteins across cancer lineages are RCN3, SULF1, and THBS2. Each is linked with FAP in more than 9 cancer types. Because this analysis shows association rather than direction, both FAP-to-partner and partner-to-FAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAP versus RCN3 in GBM, with a Pearson correlation of 0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAP→partner) and Y-score (partner→FAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCN3 →	+0.977	+0.856	<.001	<.001	3	10
OV	SULF1 →	+1.288	+1.449	<.001	<.001	3	10
OV	THBS2 →	+1.889	+1.317	<.001	<.001	3	10
BRCA	TPM4 →	+0.583	+0.799	<.001	<.001	3	10
OV	FBLN1_S147 →	+1.252	+0.898	<.001	<.001	3	10
OV	FN1 →	+1.498	+1.402	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,371 associations by consensus.

FAP vs RCN3 — GBM

Explore this scatter interactively →