Across TCGA pan-cancer cohorts, FANK1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FANK1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FANK1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FANK1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LSCC and LUAD are the cancer types where FANK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.568	1.000	.004	16	view →
LUAD	DFS	Median	All	0.771	0.237	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FANK1 tumor-vs-normal RNA expression · all FANK1 data types