Across TCGA cell cohorts, FANK1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FANK1-associated genes across cancer lineages are TGM7, C1orf185, and OR4D10. Each is linked with FANK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FANK1-to-partner and partner-to-FANK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANK1→partner) and Y-score (partner→FANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	C1orf185 →	+0.063	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4D10 →	+0.053	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.027	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

FANK1 survival (RNA) · tumor vs normal (RNA) · all FANK1 data types