Across TCGA patient cohorts, FANCF protein abundance is significantly associated with the RNA expression of many other genes, with 423 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FANCF-associated genes across cancer lineages are LRP5L, PAPLN, and RBBP8. Each is linked with FANCF in more than 1 cancer types. Because this analysis shows association rather than direction, both FANCF-to-partner and partner-to-FANCF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCF→partner) and Y-score (partner→FANCF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRP5L →	+0.776	+0.299	.001	.009	3	1
UCEC	PAPLN →	-1.078	-0.535	.004	.004	3	1
UCEC	RBBP8 →	+0.587	+0.320	.003	.005	3	1
UCEC	PGRMC1 →	+0.699	+0.305	.001	.007	3	1
UCEC	RBBP7 →	+1.260	+0.431	.009	.006	3	1
UCEC	CD40LG →	-0.710	-0.331	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 423 associations by consensus.

Exploration

FANCF survival (RNA) · tumor vs normal (RNA) · all FANCF data types