FAM98B

Across TCGA patient cohorts, FAM98B protein abundance is significantly associated with the RNA expression of many other genes, with 15,181 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM98B-associated genes across cancer lineages are EZH1, ICE2, and CDAN1. Each is linked with FAM98B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM98B-to-partner and partner-to-FAM98B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM98B versus EZH1 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98B→partner) and Y-score (partner→FAM98B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EZH1 →	+0.779	+0.278	<.001	<.001	3	7
BRCA	ICE2 →	+0.508	+0.283	<.001	<.001	3	7
HNSC	CDAN1 →	+0.715	+0.290	<.001	<.001	3	7
LSCC	ZNF287 →	+0.691	+0.295	<.001	.002	3	7
GBM	CXCL8 →	-2.469	-0.372	<.001	<.001	3	7
BRCA	PATZ1 →	+0.844	+0.292	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,181 associations by consensus.

FAM98B vs EZH1 — BRCA

Explore this scatter interactively →