FAM98A

Across TCGA cell cohorts, FAM98A mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM98A-associated genes across cancer lineages are OR4S2, GPI, and ACBD5. Each is linked with FAM98A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM98A-to-partner and partner-to-FAM98A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4S2 grouped by FAM98A-low versus FAM98A-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98A→partner) and Y-score (partner→FAM98A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR4S2 →	+0.020	+5.285	<.001	.003	3	1
LARGE_INTESTINE	GPI →	+0.518	+3.502	.007	.001	3	1
LARGE_INTESTINE	ACBD5 →	+0.741	+3.502	.004	.001	3	1
LARGE_INTESTINE	C1QBP →	+0.695	+2.451	.001	.009	3	1
LARGE_INTESTINE	ATP5F1B →	+0.557	+3.502	<.001	.001	3	1
LARGE_INTESTINE	TCEANC2 →	+0.351	+2.451	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

OR4S2 by FAM98A expression — STOMACH

Explore this box plot interactively →