FAM91A3P

Across TCGA pan-cancer cohorts, FAM91A3P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FAM91A3P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher FAM91A3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM91A3P expression acts as an unfavorable survival marker, although some lineages such as KIRC and PRAD show a favorable association.

CESC, LIHC, and STAD are the cancer types where FAM91A3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Quartile	All	0.425	0.721	<.001	112	view →
LIHC	OS	Median	All	0.704	0.853	<.001	85	view →
STAD	DFS	Median	II,III,IV	0.455	0.604	.001	72	view →
SARC	DFS	Tertile	All	0.236	0.597	<.001	35	view →
ACC	OS	Median	All	0.773	0.949	.004	33	view →
UVM	DFS	Quartile	All	0.295	0.670	.001	32	view →
LUAD	OS	Quartile	All	0.151	0.503	.003	31	view →
KIRP	OS	Quartile	All	0.903	1.000	<.001	28	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	27	view →
PAAD	OS	Median	All	0.285	0.475	.020	17	view →
UCEC	DFS	Tertile	All	0.774	0.862	.008	16	view →
KIRC	DFS	Quartile	III,IV	0.510	0.246	.012	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FAM91A3P–CESC (DFS)

Open the CESC breakdown →