family with sequence similarity 91 member A3, pseudogeneGenealiases: []
Q-omics provides the consensus-scored FAM91A3P profile across patient tissues and cancer cell-line models. FAM91A3P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, FAM91A3P is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, FAM91A3P RNA expression shows 15,214 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight CESC, HNSC, and UVM as cancer lineages where FAM91A3P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FAM91A3P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FAM91A3P survival associations across molecular data types. FAM91A3P RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FAM91A3P RNA expression–survival associations across cancer types. High FAM91A3P expression shows unfavorable associations in CESC, LIHC, STAD, SARC, ACC and UVM. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CESC as the clearest survival context for FAM91A3P RNA expression.
This table summarizes FAM91A3P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for FAM91A3P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FAM91A3P shows higher tumor expression in HNSC, BLCA, BRCA, KIRP, LUSC and STAD. The HNSC box plot shows higher FAM91A3P RNA expression in tumor versus normal tissue (log2 FC = +0.073, t-test p < 0.001).
This table shows molecular features associated with FAM91A3P in patient tissues and cancer cell lines. In patient samples, FAM91A3P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
