Across TCGA pan-cancer cohorts, FAM90A28P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FAM90A28P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where FAM90A28P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM90A28P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KIRP and THCA are the cancer types where FAM90A28P tumor–normal differential expression is most reproducible.