FAM90A26

Across TCGA pan-cancer cohorts, FAM90A26 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated FAM90A26 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher FAM90A26 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM90A26 expression acts as an unfavorable survival marker, although some lineages such as LGG and MESO show a favorable association.

LGG, COAD, and BRCA are the cancer types where FAM90A26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.821	0.643	<.001	30	view →
COAD	OS	Tertile	III,IV	0.184	0.580	.008	27	view →
BRCA	DFS	Tertile	II,III,IV	0.851	0.912	.003	20	view →
KICH	DFS	Tertile	III,IV	0.030	0.797	<.001	16	view →
DLBC	OS	Quartile	All	0.110	0.776	.001	16	view →
KIRC	OS	Median	All	0.563	0.673	.006	14	view →
LUAD	DFS	Tertile	IV	0.390	0.949	.005	12	view →
KIRP	OS	Tertile	All	0.821	0.935	.018	12	view →
THYM	DFS	Tertile	All	0.714	0.971	.007	12	view →
ESCA	DFS	Tertile	IV	0.221	0.539	.046	12	view →
MESO	DFS	Median	III,IV	0.613	0.280	.031	6	view →
THCA	DFS	Median	IV	1.000	0.599	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

FAM90A26–LGG (DFS)

Open the LGG breakdown →