Across TCGA pan-cancer cohorts, FAM90A26 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FAM90A26’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where FAM90A26 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM90A26 is over-expressed in tumor.
LUAD, CHOL, and LUSC are the cancer types where FAM90A26 tumor–normal differential expression is most reproducible.