Across TCGA pan-cancer cohorts, FAM8A6P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of FAM8A6P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where FAM8A6P RNA is repressed in tumor relative to normal tissue. In most cancer types FAM8A6P is over-expressed in tumor, although a few such as KIRP and COAD show the opposite, repressed pattern.

KIRP, COAD, and BRCA are the cancer types where FAM8A6P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM8A6P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	−0.068	.002	3	view →
COAD	Male	III,IV	−0.035	.020	3	view →
BRCA	Female	All	−0.095	.027	2	view →
HNSC	All	IV	+0.034	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: FAM8A6P RNA expression & survival · all FAM8A6P data types