FAM89A

Across TCGA cell cohorts, FAM89A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,950 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM89A-associated GO terms across cancer lineages are Mitochondrial transport, Pyrimidine nucleobase catabolic process, and Thymine catabolic process. Each is linked with FAM89A in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM89A-to-partner and partner-to-FAM89A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial transport grouped by FAM89A-low versus FAM89A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM89A→partner) and Y-score (partner→FAM89A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Mitochondrial transport →	+0.091	+1.638	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Pyrimidine nucleobase catabolic process →	-0.842	-1.086	.007	.009	3	7
LUNG_NSCLC_LUSC	Thymine catabolic process →	-0.842	-1.086	.007	.009	3	7
LUNG_NSCLC_LUSC	Thymine metabolic process →	-0.842	-1.086	.007	.009	3	7
STOMACH	DNA-templated transcription initiation →	+0.055	+1.737	.004	<.001	3	6
STOMACH	mRNA catabolic process →	+0.079	+1.999	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,950 associations by consensus.

Mitochondrial transport by FAM89A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →