FAM86JP

Across TCGA patient cohorts, FAM86JP mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86JP-associated genes across cancer lineages are OR5H2, RNU6-1284P, and RNA5SP205. Each is linked with FAM86JP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86JP-to-partner and partner-to-FAM86JP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5H2 grouped by FAM86JP-low versus FAM86JP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86JP→partner) and Y-score (partner→FAM86JP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR5H2 →	+0.146	+5.771	<.001	.003	3	1
UCEC	RNU6-1284P →	+0.662	+5.186	.007	.007	3	1
UCEC	RNA5SP205 →	+0.607	+5.852	<.001	.003	3	1
UCEC	RNU6-1311P →	+0.639	+5.186	<.001	.007	3	1
UCEC	MIR7-2 →	+0.648	+5.621	<.001	.004	3	1
UCEC	TRGV11 →	+0.205	+6.335	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OR5H2 by FAM86JP expression — UCEC

Explore this box plot interactively →