FAM86JP

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM86JP mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86JP-associated genes across cancer lineages are CD8+ T-cells and CD8+ Tcm. Each is linked with FAM86JP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86JP-to-partner and partner-to-FAM86JP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by FAM86JP-low versus FAM86JP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86JP→partner) and Y-score (partner→FAM86JP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD8+ T-cells →+0.047+4.845<.001.01131
UCECCD8+ Tcm →+0.075+4.935<.001.01031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by FAM86JP expression — UCEC

Box plot of CD8+ T-cells in FAM86JP-low vs FAM86JP-high samples in UCEC.

Explore this box plot interactively →

Exploration