FAM86HP

Across TCGA patient cohorts, FAM86HP mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible FAM86HP-associated genes across cancer lineages are RNU6-840P, MTND2P26, and LINC00557. Each is linked with FAM86HP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86HP-to-partner and partner-to-FAM86HP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-840P grouped by FAM86HP-low versus FAM86HP-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86HP→partner) and Y-score (partner→FAM86HP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-840P →	+0.517	+5.186	<.001	.007	3	1
LIHC	MTND2P26 →	+0.044	+5.878	<.001	.002	3	1
LIHC	LINC00557 →	+0.034	+5.878	<.001	.002	3	1
LIHC	PABPC1P5 →	+0.264	+5.033	<.001	.009	3	1
LIHC	RNU6ATAC10P →	+0.466	+5.544	<.001	.004	3	1
LIHC	MTND4LP9 →	+0.243	+7.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

RNU6-840P by FAM86HP expression — LIHC

Explore this box plot interactively →