FAM86EP

Across TCGA patient cohorts, FAM86EP mutation is significantly associated with the RNA expression of many other genes, with 1,960 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86EP-associated genes across cancer lineages are RN7SL454P, RNA5SP410, and CA15P2. Each is linked with FAM86EP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86EP-to-partner and partner-to-FAM86EP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL454P grouped by FAM86EP-low versus FAM86EP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86EP→partner) and Y-score (partner→FAM86EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL454P →	+0.153	+1.975	<.001	<.001	3	2
UCEC	RNA5SP410 →	+0.498	+1.499	<.001	.009	3	2
SKCM	CA15P2 →	+0.035	+4.147	<.001	.008	3	2
BRCA	LINC02342 →	+0.078	+7.731	.002	.009	3	1
CESC	LINC00686 →	+0.698	+4.996	<.001	.002	3	1
CESC	RN7SL62P →	+0.112	+4.812	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,960 associations by consensus.

RN7SL454P by FAM86EP expression — UCEC

Explore this box plot interactively →