FAM86DP

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FAM86DP Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM86DP data layer compared with 23 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher FAM86DP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM86DP expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

PRAD and UCEC are the cancer types where FAM86DP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PRADDFSMedianAll0.0850.774<.0016view →
UCECDFSMedianAll1.0000.626.0442view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FAM86DP–PRAD (DFS)

Kaplan–Meier survival curve for FAM86DP mutant vs wild-type samples in PRAD.

Open the PRAD breakdown →

Exploration