FAM86C1P

Across TCGA patient cohorts, FAM86C1P mutation is significantly associated with the RNA expression of many other genes, with 867 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86C1P-associated genes across cancer lineages are MIR6726, CYCSP48, and RPS10P21. Each is linked with FAM86C1P in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86C1P-to-partner and partner-to-FAM86C1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6726 grouped by FAM86C1P-low versus FAM86C1P-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86C1P→partner) and Y-score (partner→FAM86C1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR6726 →	+0.464	+5.763	<.001	.001	3	2
SKCM	CYCSP48 →	+0.072	+4.282	.001	.009	3	2
BLCA	RPS10P21 →	+0.144	+4.680	.002	.003	3	2
BLCA	RNA5SP206 →	+0.449	+4.463	<.001	.005	3	2
BRCA	NF1P11 →	+0.161	+5.020	<.001	.009	3	1
SKCM	TAS2R16 →	+0.029	+5.634	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 867 associations by consensus.

MIR6726 by FAM86C1P expression — HNSC

Explore this box plot interactively →