FAM86C1P

Across TCGA patient cohorts, FAM86C1P mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86C1P-associated genes across cancer lineages are 14-3-3_beta, GAPDH, and Heregulin. Each is linked with FAM86C1P in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86C1P-to-partner and partner-to-FAM86C1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by FAM86C1P-low versus FAM86C1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86C1P→partner) and Y-score (partner→FAM86C1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.140	-3.571	.003	.002	3	1
UCEC	GAPDH →	+0.575	+2.459	.026	.020	3	1
UCEC	Heregulin →	-0.180	-3.459	.002	.005	3	1
UCEC	NF2 →	+0.275	+3.000	.008	.036	3	1
UCEC	p70-S6K_pT389 →	-0.255	-2.999	.005	.035	3	1
UCEC	PI3K-p85 →	+0.230	+3.179	.023	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

14-3-3_beta by FAM86C1P expression — UCEC

Explore this box plot interactively →