FAM86C1P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM86C1P RNA expression is significantly associated with the go_rna of many other GO terms, with 3,222 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM86C1P-associated GO terms across cancer lineages are Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA 5'-end processing, and Asparaginyl-tRNA aminoacylation. Each is linked with FAM86C1P in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM86C1P-to-partner and partner-to-FAM86C1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by FAM86C1P-low versus FAM86C1P-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86C1P→partner) and Y-score (partner→FAM86C1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYEndonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.145+1.166<.001<.001311
OVARYrRNA 5'-end processing →+0.132+1.148<.001<.001310
UPPER_AERODIGESTIVE_TRACTAsparaginyl-tRNA aminoacylation →+0.153+0.955.005.006310
OVARYEndonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.132+1.148<.001<.001310
BLOOD_LymphomaDNA replication →+0.071+0.655<.001<.00139
PANCREASDouble-strand break repair via break-induced replication →+0.179+0.652.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,222 associations by consensus.

Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by FAM86C1P expression — OVARY

Box plot of Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) in FAM86C1P-low vs FAM86C1P-high samples in OVARY.

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Exploration