FAM86C1P

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM86C1P mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM86C1P-associated genes across cancer lineages are ZP2, DAOA, and IFNA2. Each is linked with FAM86C1P in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86C1P-to-partner and partner-to-FAM86C1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP2 grouped by FAM86C1P-low versus FAM86C1P-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86C1P→partner) and Y-score (partner→FAM86C1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaZP2 →+0.158+4.409<.001.00531
BLOOD_LeukemiaDAOA →+0.036+4.539<.001.00731
BLOOD_LeukemiaIFNA2 →+0.511+4.705<.001.00331
BLOOD_LeukemiaPNLIPRP3 →+0.010+4.551.001.00431
BLOOD_LeukemiaCFHR2 →+0.296+4.539<.001.00731
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ZP2 by FAM86C1P expression — BLOOD_Leukemia

Box plot of ZP2 in FAM86C1P-low vs FAM86C1P-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration