FAM86B3P

Across TCGA patient cohorts, FAM86B3P mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86B3P-associated genes across cancer lineages are MIR6859-2, HNRNPCL3, and HNRNPCL4. Each is linked with FAM86B3P in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86B3P-to-partner and partner-to-FAM86B3P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6859-2 grouped by FAM86B3P-low versus FAM86B3P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86B3P→partner) and Y-score (partner→FAM86B3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6859-2 →	+0.571	+3.690	.001	.009	3	1
UCEC	HNRNPCL3 →	+0.083	+3.778	<.001	.007	3	1
UCEC	HNRNPCL4 →	+0.056	+4.442	<.001	.007	3	1
UCEC	ORC1P1 →	+0.063	+4.868	.001	.004	3	1
UCEC	MRPS11P1 →	+0.181	+3.661	.003	.009	3	1
UCEC	RPL18AP17 →	+0.397	+4.641	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MIR6859-2 by FAM86B3P expression — UCEC

Explore this box plot interactively →