FAM86B3P

Across TCGA pan-cancer cohorts, FAM86B3P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of FAM86B3P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where FAM86B3P RNA is repressed in tumor relative to normal tissue. In most cancer types FAM86B3P is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

KICH, KIRP, and COAD are the cancer types where FAM86B3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM86B3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.795	<.001	9	view →
KIRP	All	IV	+0.815	.015	6	view →
COAD	Male	All	+0.487	<.001	5	view →
HNSC	Male	IV	+0.470	.009	4	view →
CHOL	All	All	+1.247	<.001	3	view →
READ	All	All	+0.620	.004	3	view →
STAD	All	II,III,IV	+0.416	.016	2	view →
PRAD	All	All	−0.273	<.001	2	view →
KIRC	Female	IV	−0.400	.044	1	view →
THCA	All	All	−0.229	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

FAM86B3P–KICH

Open the KICH breakdown →