FAM83H

Across TCGA cell cohorts, FAM83H mutation is significantly associated with the RNA expression of many other genes, with 1,660 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM83H-associated genes across cancer lineages are FOXE3, OR2A5, and MCCD1. Each is linked with FAM83H in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM83H-to-partner and partner-to-FAM83H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXE3 grouped by FAM83H-low versus FAM83H-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83H→partner) and Y-score (partner→FAM83H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FOXE3 →	+0.061	+3.788	.002	<.001	3	3
SOFT_TISSUE	OR2A5 →	+0.013	+4.392	<.001	.004	3	2
CNS	MCCD1 →	+0.046	+3.204	<.001	.004	3	2
LARGE_INTESTINE	SEPTIN3 →	+0.961	+3.252	.005	.002	3	2
LARGE_INTESTINE	PLTP →	-1.918	-2.764	.001	.001	3	2
LARGE_INTESTINE	CTSZ →	-1.051	-2.764	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,660 associations by consensus.

FOXE3 by FAM83H expression — BLOOD_Leukemia

Explore this box plot interactively →