Across TCGA patient cohorts, FAM83G mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM83G-associated genes across cancer lineages are 14-3-3_epsilon, cIAP, and STAT5a. Each is linked with FAM83G in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83G-to-partner and partner-to-FAM83G results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83G→partner) and Y-score (partner→FAM83G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	14-3-3_epsilon →	+0.110	+3.017	.026	.019	3	2
UCEC	cIAP →	+0.140	+2.710	.005	.003	3	2
BLCA	STAT5a →	-0.650	-3.000	.010	.036	3	1
COAD	Lck →	+0.335	+3.025	.034	.019	2	2
UCEC	14-3-3_beta →	-0.094	-3.432	.010	.005	3	1
UCEC	ERK2 →	+0.159	+1.847	.024	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

FAM83G survival (RNA) · tumor vs normal (RNA) · all FAM83G data types