Across TCGA pan-cancer cohorts, FAM83G RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated FAM83G data layer compared with 8 for mutation status and 5 for mass-spec protein.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher FAM83G RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM83G expression acts as an unfavorable survival marker, although some lineages such as SCLC and READ show a favorable association.
KIRP, LGG, and LIHC are the cancer types where FAM83G RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.