Across TCGA cell cohorts, FAM83G mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM83G-associated genes across cancer lineages are DEFA3, PRAMEF4, and RBP2. Each is linked with FAM83G in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83G-to-partner and partner-to-FAM83G results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83G→partner) and Y-score (partner→FAM83G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DEFA3 →	+0.529	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	PRAMEF4 →	+0.084	+4.867	.006	.009	3	1
BLOOD_Leukemia	RBP2 →	+0.033	+3.359	.004	.002	3	1
BLOOD_Leukemia	IQCF1 →	+0.074	+3.091	<.001	.006	3	1
BLOOD_Leukemia	TBPL2 →	+0.067	+3.675	<.001	.003	3	1
BLOOD_Leukemia	KPNA7 →	+0.314	+3.474	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

FAM83G survival (RNA) · tumor vs normal (RNA) · all FAM83G data types