FAM83F

Across TCGA pan-cancer cohorts, FAM83F mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM83F data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM83F mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM83F expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

UCEC, COAD, and CCRCC are the cancer types where FAM83F mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	II,III,IV	1.000	0.353	.013	26	view →
COAD	DFS	Median	II,III,IV	1.000	0.917	.020	18	view →
CCRCC	OS	Median	III,IV	0.587	1.000	.005	17	view →
LUAD	DFS	Median	All	0.491	0.793	.009	14	view →
HNSC	DFS	Quartile	II,III,IV	0.986	0.853	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAM83F–UCEC (DFS)

Open the UCEC breakdown →