FAM83F

Across TCGA patient cohorts, FAM83F mutation is significantly associated with the RNA expression of many other genes, with 1,449 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM83F-associated genes across cancer lineages are RPS10-NUDT3, HMGB1P30, and MT1IP. Each is linked with FAM83F in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83F-to-partner and partner-to-FAM83F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS10-NUDT3 grouped by FAM83F-low versus FAM83F-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83F→partner) and Y-score (partner→FAM83F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS10-NUDT3 →	+0.232	+2.321	.003	.006	3	2
CESC	HMGB1P30 →	+0.117	+4.384	<.001	.008	3	2
SARC	MT1IP →	+0.221	+4.857	.003	.002	3	2
BRCA	LCEP1 →	+0.145	+6.268	<.001	.001	3	2
LUAD	CICP18 →	+0.030	+4.426	<.001	.006	3	2
LUAD	ZNF519P4 →	+0.252	+4.554	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,449 associations by consensus.

RPS10-NUDT3 by FAM83F expression — UCEC

Explore this box plot interactively →