FAM83F

Across TCGA patient cohorts, FAM83F mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM83F-associated genes across cancer lineages are p62 Lck ligand, PDCD4, and Shc_pY317. Each is linked with FAM83F in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83F-to-partner and partner-to-FAM83F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by FAM83F-low versus FAM83F-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83F→partner) and Y-score (partner→FAM83F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.392	+2.700	.007	.006	3	2
UCEC	PDCD4 →	-0.494	-3.160	.019	.019	3	2
SKCM	Shc_pY317 →	-0.161	-1.790	.039	.026	3	1
SKCM	c-Met_pY1235 →	+0.071	+2.182	.039	.033	2	2
UCEC	eIF4G →	+0.308	+2.321	.027	.034	3	1
UCEC	JNK2 →	+0.178	+3.009	.047	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

p62 Lck ligand by FAM83F expression — UCEC

Explore this box plot interactively →