FAM83F

Across TCGA cell cohorts, FAM83F mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM83F-associated genes across cancer lineages are CBY1, PNKD, and MSGN1. Each is linked with FAM83F in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83F-to-partner and partner-to-FAM83F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by FAM83F-low versus FAM83F-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83F→partner) and Y-score (partner→FAM83F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.749	+3.160	<.001	.006	3	1
LARGE_INTESTINE	PNKD →	+0.552	+3.125	.002	.008	3	1
LARGE_INTESTINE	MSGN1 →	+0.061	+3.023	<.001	.002	3	1
LARGE_INTESTINE	RMND1 →	+0.498	+3.067	.004	.009	3	1
LARGE_INTESTINE	TAFA1 →	+0.187	+3.009	.006	.001	3	1
LARGE_INTESTINE	MINAR2 →	+0.024	+2.560	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

CBY1 by FAM83F expression — LARGE_INTESTINE

Explore this box plot interactively →