FAM83C

Across TCGA patient cohorts, FAM83C protein abundance is significantly associated with the RNA expression of many other genes, with 9,494 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM83C-associated genes across cancer lineages are RIN3, NFATC2, and KCND1. Each is linked with FAM83C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83C-to-partner and partner-to-FAM83C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM83C versus RIN3 in HNSC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83C→partner) and Y-score (partner→FAM83C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RIN3 →	-0.458	-0.617	<.001	<.001	3	2
LSCC	NFATC2 →	-0.859	-1.378	<.001	<.001	3	2
HNSC	KCND1 →	-0.752	-0.829	<.001	<.001	3	2
HNSC	RUBCNL →	-0.550	-0.584	<.001	.002	3	2
LSCC	STARD3NL →	-0.606	-0.937	<.001	<.001	3	2
LSCC	HAS3 →	+2.039	+1.479	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,494 associations by consensus.

FAM83C vs RIN3 — HNSC

Explore this scatter interactively →