FAM83C

Across TCGA patient cohorts, FAM83C mutation is significantly associated with the RNA expression of many other genes, with 1,432 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM83C-associated genes across cancer lineages are LINC02337, SLC7A5, and SEC23A-AS1. Each is linked with FAM83C in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM83C-to-partner and partner-to-FAM83C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02337 grouped by FAM83C-low versus FAM83C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83C→partner) and Y-score (partner→FAM83C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02337 →	+0.232	+3.917	<.001	.009	3	4
LUAD	SLC7A5 →	+1.076	+2.718	<.001	.003	3	3
COAD	SEC23A-AS1 →	+0.225	+3.571	.007	.006	3	3
LUAD	GFY →	+0.581	+2.771	.005	.004	3	3
SKCM	CXCL14 →	-1.539	-2.999	<.001	<.001	3	3
SKCM	PCAT19 →	-0.378	-1.810	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,432 associations by consensus.

LINC02337 by FAM83C expression — COAD

Explore this box plot interactively →