FAM83C

Across TCGA cell cohorts, FAM83C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,076 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM83C-associated GO terms across cancer lineages are Response to steroid hormone, Negative regulation of immune response, and Actin polymerization or depolymerization. Each is linked with FAM83C in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM83C-to-partner and partner-to-FAM83C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to steroid hormone grouped by FAM83C-low versus FAM83C-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83C→partner) and Y-score (partner→FAM83C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to steroid hormone →	+0.084	+1.319	<.001	.005	3	5
LUNG_SCLC	Negative regulation of immune response →	+0.084	+0.027	<.001	.008	3	5
BONE	Actin polymerization or depolymerization →	+0.087	+0.011	.005	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of catalytic activity →	+0.063	+1.760	<.001	.005	3	5
BONE	Peptidyl-lysine oxidation →	+1.142	+0.017	.007	.002	3	5
BONE	Positive regulation of megakaryocyte differentiation →	-0.162	-0.014	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,076 associations by consensus.

Response to steroid hormone by FAM83C expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →