FAM83C-AS1

Across TCGA pan-cancer cohorts, FAM83C-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated FAM83C-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FAM83C-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM83C-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and PAAD show a favorable association.

COAD, UVM, and ACC are the cancer types where FAM83C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.422	0.613	<.001	102	view →
UVM	DFS	Median	III,IV	0.992	0.461	.003	88	view →
ACC	DFS	Median	All	0.306	0.606	.002	65	view →
KIRC	DFS	Quartile	IV	0.260	0.687	.011	56	view →
PAAD	OS	Tertile	II,III,IV	0.654	0.347	.002	41	view →
LAML	DFS	Quartile	All	0.388	0.658	.008	36	view →
SKCM	DFS	Median	III,IV	0.395	0.685	.003	35	view →
ESCA	OS	Quartile	All	0.412	0.696	.003	35	view →
THCA	DFS	Median	II,III,IV	0.768	0.902	.002	33	view →
KICH	OS	Tertile	II,III,IV	0.722	1.000	.007	27	view →
LGG	DFS	Tertile	All	0.663	0.809	.001	24	view →
PRAD	DFS	Tertile	All	0.890	0.972	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

FAM83C-AS1–COAD (DFS)

Open the COAD breakdown →