FAM83C-AS1

Across TCGA pan-cancer cohorts, FAM83C-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FAM83C-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where FAM83C-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM83C-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

LUSC, LUAD, and COAD are the cancer types where FAM83C-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM83C-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	III,IV	+0.986	<.001	9	view →
LUAD	Female	III,IV	+0.666	<.001	9	view →
COAD	Male	II,III,IV	+0.485	<.001	9	view →
KICH	Male	II,III,IV	−0.558	<.001	8	view →
LIHC	Male	All	+0.464	<.001	7	view →
BRCA	All	III,IV	+0.318	<.001	6	view →
UCEC	All	All	+0.507	<.001	4	view →
CHOL	Male	All	+0.950	.005	2	view →
KIRC	All	All	−0.110	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

FAM83C-AS1–LUSC

Open the LUSC breakdown →