FAM83B

Across TCGA patient cohorts, FAM83B protein abundance is significantly associated with the RNA expression of many other genes, with 13,997 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM83B-associated genes across cancer lineages are RGS22, AFF3, and KCNK1. Each is linked with FAM83B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM83B-to-partner and partner-to-FAM83B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM83B versus RGS22 in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83B→partner) and Y-score (partner→FAM83B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RGS22 →	-1.020	-0.712	<.001	<.001	3	5
BRCA	AFF3 →	-1.857	-0.803	<.001	<.001	3	5
BRCA	KCNK1 →	+1.199	+0.510	.001	.007	3	4
BRCA	CFAP91 →	-0.738	-0.681	<.001	<.001	3	4
HNSC	ANGPTL5 →	-0.436	-0.513	<.001	<.001	3	4
LSCC	GJB5 →	+1.569	+0.688	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,997 associations by consensus.

FAM83B vs RGS22 — BRCA

Explore this scatter interactively →