FAM83B

Across TCGA cell cohorts, FAM83B mutation is significantly associated with the RNA expression of many other genes, with 182 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM83B-associated genes across cancer lineages are OR8B12, FAM86B1, and TWF2. Each is linked with FAM83B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM83B-to-partner and partner-to-FAM83B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B12 grouped by FAM83B-low versus FAM83B-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83B→partner) and Y-score (partner→FAM83B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	OR8B12 →	+0.054	+4.000	<.001	.002	3	2
LARGE_INTESTINE	FAM86B1 →	+1.166	+3.169	<.001	.009	3	2
LARGE_INTESTINE	TWF2 →	+0.857	+3.364	<.001	.002	3	2
BLOOD_Myeloma	ASZ1 →	+0.163	+4.700	<.001	<.001	3	1
BLOOD_Myeloma	OR56B1 →	+0.034	+4.070	<.001	.001	3	1
BLOOD_Myeloma	OR52B6 →	+0.110	+3.285	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

OR8B12 by FAM83B expression — BLOOD_Myeloma

Explore this box plot interactively →