Across TCGA patient cohorts, FAM78B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,591 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FAM78B-associated proteins across cancer lineages are NRP2, TAGLN2, and CDH1. Each is linked with FAM78B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM78B-to-partner and partner-to-FAM78B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM78B→partner) and Y-score (partner→FAM78B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NRP2 →	+0.738	+1.145	<.001	<.001	3	5
LSCC	TAGLN2 →	+0.342	+0.311	<.001	<.001	3	5
HNSC	CDH1 →	-0.577	-0.551	<.001	<.001	3	5
OV	AEBP1 →	+0.740	+0.494	<.001	.002	3	5
LSCC	FHL3 →	+0.515	+0.301	<.001	<.001	3	5
UCEC	FMNL3 →	+0.311	+0.457	.008	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,591 associations by consensus.

Exploration

FAM78B survival (RNA) · tumor vs normal (RNA) · all FAM78B data types