Across TCGA patient cohorts, FAM78B mutation is significantly associated with the RNA expression of many other genes, with 608 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM78B-associated genes across cancer lineages are MAP6D1, VARS1, and RN7SL794P. Each is linked with FAM78B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM78B-to-partner and partner-to-FAM78B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM78B→partner) and Y-score (partner→FAM78B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP6D1 →	+0.571	+3.721	.001	<.001	3	2
UCEC	VARS1 →	+0.406	+2.415	.008	.003	3	2
UCEC	RN7SL794P →	+0.285	+1.891	<.001	.004	3	2
UCEC	SNAI3-AS1 →	+0.344	+3.353	.001	.005	3	2
UCEC	TIPIN →	+0.522	+2.711	<.001	.003	3	2
LUAD	E2F6P2 →	+0.040	+3.744	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 608 associations by consensus.

Exploration

FAM78B survival (RNA) · tumor vs normal (RNA) · all FAM78B data types