FAM78A

Across TCGA patient cohorts, FAM78A protein abundance is significantly associated with the RNA expression of many other genes, with 9,453 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FAM78A-associated genes across cancer lineages are LILRB1, SELENOI, and WDPCP. Each is linked with FAM78A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM78A-to-partner and partner-to-FAM78A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM78A versus LILRB1 in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM78A→partner) and Y-score (partner→FAM78A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LILRB1 →	+1.402	+0.487	.001	.001	3	3
HNSC	SELENOI →	-1.279	-0.816	<.001	<.001	3	3
HNSC	WDPCP →	-0.792	-0.894	<.001	<.001	3	3
HNSC	ETAA1 →	-0.866	-1.010	.004	<.001	3	3
HNSC	MTFR2P1 →	-1.191	-0.816	<.001	<.001	3	3
GBM	NFAM1 →	+1.484	+0.506	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,453 associations by consensus.

FAM78A vs LILRB1 — GBM

Explore this scatter interactively →