FAM78A

Across TCGA patient cohorts, FAM78A mutation is significantly associated with the RNA expression of many other genes, with 1,809 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM78A-associated genes across cancer lineages are MIR4797, KLRC3, and TRDV1. Each is linked with FAM78A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM78A-to-partner and partner-to-FAM78A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4797 grouped by FAM78A-low versus FAM78A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM78A→partner) and Y-score (partner→FAM78A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR4797 →	+0.482	+5.186	<.001	.007	3	2
UCEC	KLRC3 →	+0.080	+1.495	.006	.009	3	2
UCEC	TRDV1 →	+0.499	+2.132	<.001	<.001	3	2
COAD	RNU6-275P →	+0.252	+5.412	<.001	.001	3	2
COAD	TRAJ57 →	+0.510	+3.542	.001	.005	3	2
LUAD	RNA5SP213 →	+0.522	+5.343	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,809 associations by consensus.

MIR4797 by FAM78A expression — LIHC

Explore this box plot interactively →