FAM76B

Across TCGA patient cohorts, FAM76B mutation is significantly associated with the RNA expression of many other genes, with 1,822 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM76B-associated genes across cancer lineages are RN7SL134P, AQP7P3, and IGHV1-69D. Each is linked with FAM76B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM76B-to-partner and partner-to-FAM76B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by FAM76B-low versus FAM76B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM76B→partner) and Y-score (partner→FAM76B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.154	+2.484	<.001	.001	3	2
UCEC	AQP7P3 →	+0.029	+3.167	<.001	.005	3	1
UCEC	IGHV1-69D →	+1.971	+3.584	<.001	.002	3	1
UCEC	ARRDC3-AS1 →	+0.230	+2.533	.008	.009	3	1
UCEC	MIR1291 →	+0.520	+1.928	.001	.009	3	1
HNSC	MIR544A →	+0.318	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,822 associations by consensus.

RN7SL134P by FAM76B expression — UCEC

Explore this box plot interactively →