FAM76B

Across TCGA cell cohorts, FAM76B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,243 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM76B-associated GO terms across cancer lineages are Microtubule organizing center organization, Positive regulation of DNA metabolic process, and RNA-templated DNA biosynthetic process. Each is linked with FAM76B in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM76B-to-partner and partner-to-FAM76B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by FAM76B-low versus FAM76B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM76B→partner) and Y-score (partner→FAM76B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Microtubule organizing center organization →	+0.086	+1.070	<.001	<.001	3	16
BONE	Positive regulation of DNA metabolic process →	+0.073	+0.922	.001	<.001	3	16
OVARY	RNA-templated DNA biosynthetic process →	+0.088	+0.890	<.001	.002	3	15
LUNG_SCLC	Centrosome cycle →	+0.095	+1.137	<.001	<.001	3	15
LUNG_SCLC	Centriole replication →	+0.110	+0.881	<.001	<.001	3	15
SKIN	Positive regulation of chromosome organization →	+0.077	+0.974	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,243 associations by consensus.

Microtubule organizing center organization by FAM76B expression — LUNG_SCLC

Explore this box plot interactively →