FAM74A4

Across TCGA patient cohorts, FAM74A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,101 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM74A4-associated GO terms across cancer lineages are Protein depalmitoylation, Cytoplasmic pattern recognition receptor signaling pathway, and Respiratory system development. Each is linked with FAM74A4 in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM74A4-to-partner and partner-to-FAM74A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depalmitoylation grouped by FAM74A4-low versus FAM74A4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM74A4→partner) and Y-score (partner→FAM74A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein depalmitoylation →	+0.082	+0.014	<.001	<.001	3	6
STAD	Cytoplasmic pattern recognition receptor signaling pathway →	+0.073	+0.014	<.001	<.001	3	6
STAD	Respiratory system development →	+0.067	+0.012	<.001	<.001	3	6
OV	Motile cilium assembly →	+0.067	+0.011	<.001	<.001	3	6
LUAD	Specification of symmetry →	+0.046	+0.008	<.001	<.001	3	6
LUAD	Microtubule bundle formation →	+0.092	+0.006	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,101 associations by consensus.

Protein depalmitoylation by FAM74A4 expression — STAD

Explore this box plot interactively →