Across TCGA pan-cancer cohorts, FAM74A1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated FAM74A1 data layer.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher FAM74A1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM74A1 expression acts as an unfavorable survival marker.
STAD, COAD, and LGG are the cancer types where FAM74A1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.