Across TCGA pan-cancer cohorts, FAM74A1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FAM74A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where FAM74A1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM74A1 is over-expressed in tumor.

KICH are the cancer types where FAM74A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM74A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	+0.120	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM74A1 RNA expression & survival · all FAM74A1 data types